Classifying mild traumatic brain injuries with functional network analysis
نویسندگان
چکیده
منابع مشابه
Analysis of functional pathways altered after mild traumatic brain injury.
Concussive injury (or mild traumatic brain injury; mTBI) can exhibit features of focal or diffuse injury patterns. We compared and contrasted the cellular and molecular responses after mild controlled cortical impact (mCCI; a focal injury) or fluid percussion injury (FPI; a diffuse injury) in rats. The rationale for this comparative analysis was to investigate the brain's response to mild diffu...
متن کاملFunctional connectivity in mild traumatic brain injury.
OBJECTIVES Research suggests that the majority of mild traumatic brain injury (mTBI) patients exhibit both cognitive and emotional dysfunction within the first weeks of injury, followed by symptom resolution 3-6 months postinjury. The neuronal correlates of said dysfunction are difficult to detect with standard clinical neuroimaging, complicating differential diagnosis and early identification ...
متن کاملExperimental Mild Traumatic Brain Injury Induces Functional
25 26 It is estimated that about 1.5 million Americans suffer a traumatic brain injury (TBI) every year, of which 27 approximately 80% are considered mild injuries. Because symptoms caused by mild TBI last less than half an 28 hour by definition and apparently resolve without treatment, the study of mild TBI is often neglected resulting in 29 a significant knowledge-gap for this wide-spread pro...
متن کاملGraph Analysis of Functional Brain Networks in Patients with Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) is one of the most common neurological disorders worldwide. Posttraumatic complaints are frequently reported, interfering with outcome. However, a consistent neural substrate has not yet been found. We used graph analysis to further unravel the complex interactions between functional brain networks, complaints, anxiety and depression in the sub-acute stage aft...
متن کاملMild traumatic brain injuries: a 10-year follow-up.
OBJECTIVE AND DESIGN Long-term consequences of mild traumatic brain injuries were investigated based on a 10-year follow-up of patients from a previously-published randomized controlled study of mild traumatic brain injuries. One aim was to describe changes over time after mild traumatic brain injuries in terms of the extent of persisting post-concussion symptoms, life satisfaction, perceived h...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2018
ISSN: 1752-0509
DOI: 10.1186/s12918-018-0645-z